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Retinopathy After Diabetes Onset Diabetes retinopathy (DR) refers to any of the vascular changes in the retina. These are observed clinically as microaneurysms, dot and blot hemorrhages, edema, hard and soft exudates, neovascularization and newly formed fibrovascular tissue. The major sight-threatening manifestations of DR, macular edema and proliferative diabetes retinopathy, PDR, are the end res

https://www.ludc.lu.se/research/diabetes-and-celiac-disease/research-projects/read - 2026-10-29

DOHK

Diabetes and cardiovascular risk factors DOHK is the acronym for the Swedish Diabetes och Hjärta-Kärl.   Patients diagnosed with diabetes have an increased risk to develop cardiovascular complications such as acute myocardial infarction (AMI) and stroke. Up to today, about 30 different genes have been identified as predisposing for type 1 diabetes. Furthermore, about 60 different genes have shown

https://www.ludc.lu.se/research/diabetes-and-celiac-disease/research-projects/dohk - 2026-10-29

Darbaz Awla

Current position Post-doctoral fellow (MD, PhD). Surgery Research Unit, Department of Clinical Sciences, Malmö. Thesis title Signaling and adhesive mechanisms in akute pancreatitis. List of papers included Awal D , Abdulla A, Regnér S and Thorlacius H. TLR4 but not TLR2 regulates inflammation, and tissuew damage in acute pancreatitis induced by retrograde infrusion of taurocholate. Inflamm, Res. 2

https://www.ludc.lu.se/research-0/diabetic-complications/lab-alumni/darbaz-awla - 2026-10-29

Anna Åkerud

Current position Resulatory Affairs Associate at Trial Form Support Thesis title Uterine remodeling during pregnancy; Sstudies on the effect of Heparin/Heparan Sulfate List of papers included E. Malmström, M. Sennström, A. Holmberg, H. Frielingsdorf, E. Eklund, L. Malmström, E. Tufvesson, M.F. Gomez, G. Westergren-Thorsson, Ekman-Ordeberg andA. Malmström. The importance of fibroblasts in remodelli

https://www.ludc.lu.se/research-0/diabetic-complications/lab-alumni/anna-akerud - 2026-10-29

Jenny Öhman

Current position Project leader, Cardiology Department, Lund University http://www.med.lu.se/english/klinvetlund/cardiology/research/project_leaders/oehman Thesis title Diabetic Vascular Complications & Inflammation Role of NFAT and TNFα List of papers included J.Nilsson, L M Nilsson, Y W Chen, J D Molkentn, D Erlinge & M F Gomez. High glucose activates Nuclear Factor of Activated T-cells (NFAT) i

https://www.ludc.lu.se/research-0/diabetic-complications/lab-alumni/jenny-ohman - 2026-10-29

Group members

Team members Jens Lagerstedt, PhD, PI Claire Lyons, associate researcher Kristina Nordén, PhD, postdoc Rita Del Giudice, PhD, postdoc Shelley Edmunds, PhD, postdoc Claire Lyons,  PhD, postdoc Oktawia Nilsson-Wolanin, MSc, PhD student Raquel Lopera, student Manca Mohar, Master student   Alumni Jonathan dalla-Riva, PhD Jitka Petrlova, PhD Karin Stenkula, PhD Tatu Haataja, PhD

https://www.ludc.lu.se/research/medical-protein-science/group-members - 2026-10-29

Diabetic Complications

Department of Clinical Sciences Malmö PI: Maria Gomez Head: Maria F. Gomez Diabetes mellitus is a lifelong, incapacitating disease affecting multiple organs. Worldwide prevalence figures estimate that there will be 380 million diabetic patients in 2025. Presently, diabetes can neither be prevented nor cured and the disease is associated with devastating chronic complications including coronary hea

https://www.ludc.lu.se/research/diabetic-complications - 2026-10-29

Vascular complications of diabetes: Studies on NFAT

Vascular complications of diabetes: Studies on NFAT (Nuclear Factor of Activated T-cells) as a novel target for the treatment of atherosclersis and vascular dysfunction in diabetes. Diabetes-induced macro- and microvascular complications are the major cause of morbidity and mortality in diabetic patients. Based on current trends, the rising incidence of diabetes (expected to reach 380 million peop

https://www.ludc.lu.se/research/diabetic-complications/research-areas/vascular-complications-diabetes-studies-nfat - 2026-10-29

Role of the incretin hormone GIP

Role of the incretin hormone GIP in the development of diabetic vascular complications - good or bad? The incretin hormones GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) are released from the intestine after food ingestion to stimulate insulin secretion in a glucose-dependent manner. Both GIP and GLP-1 are rapidly degraded by the enzyme dipeptidyl peptidase

https://www.ludc.lu.se/research/diabetic-complications/research-areas/role-incretin-hormone-gip - 2026-10-29

Work package 4 of SUMMIT

Work package 4 of SUMMIT - "Novel animal models of diabetes" Novel means to prevent diabetic complications are needed. An important mean in this undertaking would be to develop tools which would make development of novel drugs for prevention of complications more feasible. The SUMMIT consortium brings together European key leaders in the field of diabetes research; scientists with a deep insight i

https://www.ludc.lu.se/research/diabetic-complications/research-areas/work-package-4-summit - 2026-10-29

Helena Malm

Transcriptional regulation of miRNA-212 and miRNA-132 and their fine-tuning function of beta cell insulin secretion Type 2 diabetes is characterized by hyperglycemia due to insulin resistance in the target tissue and insufficient insulin secretion from the beta cells. Finding new mechanisms and pathways involved in the regulation of insulin secretion from the pancreatic beta cells is of great impo

https://www.ludc.lu.se/education-training/theses/theses-2016/helena-malm - 2026-10-29

Caroline Montén

In search of the missing heritability of celiac disease, from genome-wide linkage & associaiton to a candidate gene approach Celiac diseasd ia a gluten dependent enteropathy of the small intestine, associated with the HLA DQ2 and DQ8 haplotypes and tissue transglutaminase autoantibodies (tTGA). About 40% of the population carries these HLA risk haplotypes, but only 1-3% develoops celias disease. A

https://www.ludc.lu.se/education-training/theses/theses-2016/caroline-monten - 2026-10-29

Welcome to Lund University Diabetes Centre

Lund University Diabetes Centre, LUDC, is a consortium of research groups at Lund University dedicated to unravelling the pathogenesis and treatment of diabetes mellitus. LUDC started July 1st 2006 when selected for funding by the Swedish Research Council (Vetenskapsrådet) in fierce national competition, as a part of the call for applications for Linneaus grants. We are active in several different

https://www.ludc.lu.se/about-us/welcome-lund-university-diabetes-centre - 2026-10-29